But most of the existing human microbiome work in China consists of small to medium-sized studies in specific regions and focusing on the gut microbiome, such as the Guangzhou Nutrition and Health Study and the Guangdong Gut Microbiome Project. This calls for the country to launch its own large-size cohort study to map the microbiome of its population. Nature Spotlight: Nutrition research in ChinaĬhina contains a huge number of populations with diverse diets, cultures and lifestyles. The results will be immensely valuable to clinical researchers in those locations. Researchers from both the United States and Europe have established large-scale cohort studies - such as the American Gut Project and Dutch Microbiome Project - to comprehensively capture microbiome profiles in these regions. Using a microbiome survey from North America, say, to draw conclusions for an Asian population probably won’t work. But my microbiome is not the same as yours: microbiomes are shaped by environmental factors such as diet, lifestyle, genetics and ethnicity. Launched in 2007, the HMP was based on a small group of only 242 people, from two US cities: St Louis in Missouri, and Houston in Texas. This work has already contributed to disease prevention and prediction, and to precision treatment - and is likely to become even more prominent in future therapies.Īs powerful as the HMP was, the data it generated have limitations. These projects to map the human microbiome have proved hugely valuable, helping to lay the foundation for further investigation and discovery of core microbial biomarkers. The landmark US National Institutes of Health-funded Human Microbiome Project (HMP), and its follow-up, the Integrative Human Microbiome Project (iHMP), increased our understanding of how the microbiome affected human health.
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